You guys are really over thinking this. As much as we would like to think, fish simply are not capable of thought or reason. They have no idea of what a hook or lure is, or if looks natural, or if it's the right color. A fishes reaction to a lure is simply instinctual. If a fish is hungry and a lure acts alive and reacts in a certain way, under certain conditions, the fish will take it, regardless of shape or color. It's absurd to think a fish will take or refuse a lure by it's color or shape. How many real live, chartruese colored shad or live grape sparkle, neon striped, fluorescence pink tailed colored nightcrawlers does a fish see in it's lifetime. Not many, I think. Does the hungry fish think, as the grape sparkle, neon striped, fluorescence pink tailed worm swims by. "No! I think I will wait for the natural looking one to come by".